The second half of this verse is the part that catches my eye. I want God to give me the desires of my heart. On the surface, I think about how easy my life would be if that happened. But of course I shouldn't really read the second half of the verse until I've given thought to the first half. Those who live lives of ease or selfish pleasure are not generally not those who "take delight in the Lord." Clearly, then, if I truly delight in God, then the desires of my heart will not be the things that characterize the rich and beautiful and famous (though wealth and beauty and good looks do not of themselves prevent people from having spiritual priorities). If my delight is in God, then my heart's desire will be in serving God, making peace, working for justice, and sharing unconditional love and forgiveness.
Make me delight in your Name, O God, and may my deepest desire be the doing of your will; in Jesus' Name. Amen.